All cars wheel fitment and tire size guide

Mercedes S-Klasse (W221) wheel sizes

Year	Wheel size	Offset	Bolt pattern	Tire size
Mercedes S-Klasse (W221) S320
2006	17x8.0	43	5x112	235/55R17
2007	17x8.0	43	5x112	235/55R17
2008	17x8.0	43	5x112	235/55R17
2009	17x8.0	43	5x112	235/55R17
2010	17x8.0	43	5x112	235/55R17
2011	17x8.0	43	5x112	235/55R17
2012	17x8.0	43	5x112	235/55R17
2013	17x8.0	43	5x112	235/55R17
Mercedes S-Klasse (W221) S350
2006	17x8.0	43	5x112	235/55R17
2007	17x8.0	43	5x112	235/55R17
2008	17x8.0	43	5x112	235/55R17
2009	17x8.0	43	5x112	235/55R17
2010	17x8.0	43	5x112	235/55R17
2011	17x8.0	43	5x112	235/55R17
2012	17x8.0	43	5x112	235/55R17
2013	17x8.0	43	5x112	235/55R17
Mercedes S-Klasse (W221) S500
2006	18x8.5	43	5x112	255/45R18
2006	18x8.5	43	5x112	275/45R18
2007	18x8.5	43	5x112	275/45R18
2007	18x8.5	43	5x112	255/45R18
2008	18x8.5	43	5x112	255/45R18
2008	18x8.5	43	5x112	275/45R18
2009	18x8.5	43	5x112	255/45R18
2009	18x8.5	43	5x112	275/45R18
2010	18x8.5	43	5x112	255/45R18
2010	18x8.5	43	5x112	275/45R18
2011	18x8.5	43	5x112	255/45R18
2011	18x8.5	43	5x112	275/45R18
2012	18x8.5	43	5x112	275/45R18
2012	18x8.5	43	5x112	255/45R18
2013	18x8.5	43	5x112	255/45R18
2013	18x8.5	43	5x112	275/45R18
Mercedes S-Klasse (W221) S600
2006	18x8.5	43	5x112	255/45R18 front
2006	18x9.5	43	5x112	275/45R18 rear
2007	18x8.5	43	5x112	255/45R18 front
2007	18x9.5	43	5x112	275/45R18 rear
2008	18x8.5	43	5x112	255/45R18 front
2008	18x9.5	43	5x112	275/45R18 rear
2009	18x8.5	43	5x112	255/45R18 front
2009	18x9.5	43	5x112	275/45R18 rear
2010	18x8.5	43	5x112	255/45R18 front
2010	18x9.5	43	5x112	275/45R18 rear
2011	18x8.5	43	5x112	255/45R18 front
2011	18x9.5	43	5x112	275/45R18 rear
2012	18x8.5	43	5x112	255/45R18 front
2012	18x9.5	43	5x112	275/45R18 rear
2013	18x8.5	43	5x112	255/45R18 front
2013	18x9.5	43	5x112	275/45R18 rear

Wheel size Mercedes S-Klasse (W221):
PCD 5x112 diametr for 17 to 18, width for 8J to 9.5J, offset 43. Similar to Mercedes S-Class (W222) S 500 4-matic 2018

Tire size 17 to 18, width 235 to 275 and tire aspect 45 to 55.
Smallest tire size: 255/45R18, Largest: 275/45R18.